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LMX1A antibody - middle region
Instruction Manual!
| Product name: | LMX1A antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-LMX1A polyclonal antibody - middle region
Catalog Number：IC105583
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Product Profile
| ProductName | Rabbit anti-LMX1A polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-LMX1A antibody: synthetic peptide directed towards the middle region of human LMX1A |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | LMX1A |
|---|---|
| Gene Synonyms |
LMX-1
More
LMX1 LMX1.1 MGC87616 |
| Gene Full Name | LIM homeobox transcription factor 1, alpha |
| Gene Summary |
Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin. Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-199 AL160058.8 14249-14447 c 200-2447 AK127724.1 362-2609 2448-3382 AL390730.12 9415-10349 c
More
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| Alternative Names |
LMX-1
More
LMX1 LMX1.1 MGC87616 |
| MolecularWeight(MW) | 43kDa |
| Sequence | 382 amino acids |
Database Links
| Entrez Gene | 4009 |
|---|---|
| SwissProt ID | Q8TE12 |
| Protein Accession | NP_796372 |
Application
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Immunohistochemical
Rabbit Anti-LMX1A AntibodyParaffin Embedded Tissue: Human MuscleCellular Data: Skeletal muscle cellsAntibody Concentration: 4.0-8.0 ug/mlMagnification: 400X
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Western blot
Host: Rabbit
Target Name: TRIM10
Sample Tissue: 721_B
Antibody Dilution: 1.0ug/ml -
Western blot
Host: Rabbit
Target Name: LMX1A
Sample Tissue: MCF7
Antibody Dilution: 1.0ug/ml -
Western blot
Titration: 1 ug/ml
Positive Control: 721_B Whole Cell
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
