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PAWR antibody - middle region

PAWR antibody - middle region PAWR antibody - middle region

Instruction Manual!

Product name: PAWR antibody - middle region
Source:Rabbit
Purity:>95%
Buffer Formulation:phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WBIHC
Storage:Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
UOM:100ug

Rabbit anti-PAWR polyclonal antibody - middle region

Catalog Number:IC105618

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Product Profile

ProductName Rabbit anti-PAWR polyclonal antibody - middle region
AntibodyType Primary Antibodies
Immunogen
The immunogen for anti-PAWR antibody: synthetic peptide directed towards the middle region of human PAWR

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHC

Species Reactivity

DogGuinea PigHumanMousePigRabbitRat

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol PAWR
Gene Synonyms
PAR4
Par-4
Gene Full Name PRKC, apoptosis, WT1, regulator
Gene Summary
The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
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Alternative Names
PAR4
Par-4
MolecularWeight(MW)  37kDa
Sequence 340 amino acids

Database Links

Entrez Gene 5074
SwissProt ID O75796
Protein Accession NP_002574

Application

  • Immunohistochemical
  • Western blot

    0.2-1 ug/ml
    Positive Control: Jurkat cell lysate

  • Western blot

    Positive Control: Lane 1: 30ug rat striatum homogenate
    Primary Antibody Dilution : 1:1000
    Secondary Antibody : Anti rabbit-HRP 
    Secondry Antibody Dilution : 1:10,000
    Submitted by: Kristy Shimp, University of Florida

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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