PAWR antibody - middle region
Product name: | PAWR antibody - middle region |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WBIHC |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-PAWR polyclonal antibody - middle region
Catalog Number:IC105618
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Product Profile
ProductName | Rabbit anti-PAWR polyclonal antibody - middle region |
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AntibodyType | Primary Antibodies |
Immunogen |
The immunogen for anti-PAWR antibody: synthetic peptide directed towards the middle region of human PAWR |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | PAWR |
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Gene Synonyms |
PAR4
Par-4 |
Gene Full Name | PRKC, apoptosis, WT1, regulator |
Gene Summary |
The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
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Alternative Names |
PAR4
Par-4 |
MolecularWeight(MW) | 37kDa |
Sequence | 340 amino acids |
Database Links
Entrez Gene | 5074 |
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SwissProt ID | O75796 |
Protein Accession | NP_002574 |
Application
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Immunohistochemical
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Western blot
0.2-1 ug/ml
Positive Control: Jurkat cell lysate -
Western blot
Positive Control: Lane 1: 30ug rat striatum homogenate
Primary Antibody Dilution : 1:1000
Secondary Antibody : Anti rabbit-HRP
Secondry Antibody Dilution : 1:10,000
Submitted by: Kristy Shimp, University of Florida
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.