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SMAD7 antibody - N-terminal region
Instruction Manual!
| Product name: | SMAD7 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-SMAD7 polyclonal antibody - N-terminal region
Catalog Number：IC105599
Product Profile
| ProductName | Rabbit anti-SMAD7 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-SMAD7 antibody: synthetic peptide directed towards the N terminal of human SMAD7 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | SMAD7 |
|---|---|
| Gene Synonyms |
CRCS3
More
MADH7 MADH8 |
| Gene Full Name | SMAD family member 7 |
| Gene Summary |
Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
More
|
| Alternative Names |
CRCS3
More
MADH7 MADH8 |
| MolecularWeight(MW) | 46kDa |
| Sequence | 426 amino acids |
Database Links
| Entrez Gene | 4092 |
|---|---|
| SwissProt ID | O15105 |
| Protein Accession | NP_005895 |
Application
-
Western blot
Positive Control: Lane 1: 2ug Flag-SMAD7 transfected 293 extracts
Primary Antibody Dilution : 1:500
Secondary Antibody : Goat anti-rabbit-HRP
Secondry Antibody Dilution : 1:5000
Submitted by: Anonymous
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
